Cargando…
Rapid Evolution of HERC6 and Duplication of a Chimeric HERC5/6 Gene in Rodents and Bats Suggest an Overlooked Role of HERCs in Mammalian Immunity
Studying the evolutionary diversification of mammalian antiviral defenses is of main importance to better understand our innate immune repertoire. The small HERC proteins are part of a multigene family, including HERC5 and HERC6, which have probably diversified through complex evolutionary history i...
Autores principales: | Jacquet, Stéphanie, Pontier, Dominique, Etienne, Lucie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775381/ https://www.ncbi.nlm.nih.gov/pubmed/33391270 http://dx.doi.org/10.3389/fimmu.2020.605270 |
Ejemplares similares
-
HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases
por: García-Cano, Jesús, et al.
Publicado: (2019) -
The Downregulation of Both Giant HERCs, HERC1 and HERC2, Is an Unambiguous Feature of Chronic Myeloid Leukemia, and HERC1 Levels Are Associated with Leukemic Cell Differentiation
por: Ali, Muhammad Shahzad, et al.
Publicado: (2022) -
HERC Ubiquitin Ligases in Cancer
por: Sala-Gaston, Joan, et al.
Publicado: (2020) -
Large HERCs Function as Tumor Suppressors
por: Schneider, Taiane, et al.
Publicado: (2019) -
The expression and clinical significance of HERC4 in breast cancer
por: Zhou, Hui, et al.
Publicado: (2013)