Whole-genome sequencing of recurrent neuroblastoma reveals somatic mutations that affect key players in cancer progression and telomere maintenance

Neuroblastoma is the most common and deadly childhood tumor. Relapsed or refractory neuroblastoma has a very poor prognosis despite recent treatment advances. To investigate genomic alterations associated with relapse and therapy resistance, whole-genome sequencing was performed on diagnostic and re...

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Detalles Bibliográficos
Autores principales: Fransson, Susanne, Martinez-Monleon, Angela, Johansson, Mathias, Sjöberg, Rose-Marie, Björklund, Caroline, Ljungman, Gustaf, Ek, Torben, Kogner, Per, Martinsson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775426/
https://www.ncbi.nlm.nih.gov/pubmed/33384420
http://dx.doi.org/10.1038/s41598-020-78370-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775426/
https://www.ncbi.nlm.nih.gov/pubmed/33384420
http://dx.doi.org/10.1038/s41598-020-78370-7

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