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The transcription factor OpWRKY2 positively regulates the biosynthesis of the anticancer drug camptothecin in Ophiorrhiza pumila

The limited bioavailability of plant-derived natural products with anticancer activity poses major challenges to the pharmaceutical industry. An example of this is camptothecin, a monoterpene indole alkaloid with potent anticancer activity that is extracted at very low concentrations from woody plan...

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Detalles Bibliográficos
Autores principales: Hao, Xiaolong, Xie, Chenhong, Ruan, Qingyan, Zhang, Xichen, Wu, Chao, Han, Bing, Qian, Jun, Zhou, Wei, Nützmann, Hans-Wilhelm, Kai, Guoyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775441/
https://www.ncbi.nlm.nih.gov/pubmed/33384421
http://dx.doi.org/10.1038/s41438-020-00437-3