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The transcription factor OpWRKY2 positively regulates the biosynthesis of the anticancer drug camptothecin in Ophiorrhiza pumila
The limited bioavailability of plant-derived natural products with anticancer activity poses major challenges to the pharmaceutical industry. An example of this is camptothecin, a monoterpene indole alkaloid with potent anticancer activity that is extracted at very low concentrations from woody plan...
Autores principales: | Hao, Xiaolong, Xie, Chenhong, Ruan, Qingyan, Zhang, Xichen, Wu, Chao, Han, Bing, Qian, Jun, Zhou, Wei, Nützmann, Hans-Wilhelm, Kai, Guoyin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775441/ https://www.ncbi.nlm.nih.gov/pubmed/33384421 http://dx.doi.org/10.1038/s41438-020-00437-3 |
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