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The Role of CaMKII Overexpression and Oxidation in Atrial Fibrillation—A Simulation Study

This simulation study aims to investigate how the Calcium/calmodulin-dependent protein kinase II (CaMKII) overexpression and oxidation would influence the cardiac electrophysiological behavior and its arrhythmogenic mechanism in atria. A new-built CaMKII oxidation module and a refitted CaMKII overex...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Shen, Weijian, Zhang, Shanzhuo, Luo, Gongning, Wang, Kuanquan, Xu, Yong, Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775483/
https://www.ncbi.nlm.nih.gov/pubmed/33391023
http://dx.doi.org/10.3389/fphys.2020.607809