The V617I Substitution in Avian Coronavirus IBV Spike Protein Plays a Crucial Role in Adaptation to Primary Chicken Kidney Cells

The naturally isolated avian coronavirus infectious bronchitis virus (IBV) generally cannot replicate in chicken kidney (CK) cells. To explore the molecular mechanism of IBV adapting to CK cells, a series of recombinant viruses were constructed by chimerizing the S genes of CK cell-adapted strain H1...

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Detalles Bibliográficos
Autores principales: Jiang, Yi, Gao, Mingyan, Cheng, Xu, Yu, Yan, Shen, Xinyue, Li, Jianmei, Zhou, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775488/
https://www.ncbi.nlm.nih.gov/pubmed/33391226
http://dx.doi.org/10.3389/fmicb.2020.604335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775488/
https://www.ncbi.nlm.nih.gov/pubmed/33391226
http://dx.doi.org/10.3389/fmicb.2020.604335

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