Cargando…
Pharmaco-Optogenetic Targeting of TRPC Activity Allows for Precise Control Over Mast Cell NFAT Signaling
Canonical transient receptor potential (TRPC) channels are considered as elements of the immune cell Ca(2+) handling machinery. We therefore hypothesized that TRPC photopharmacology may enable uniquely specific modulation of immune responses. Utilizing a recently established TRPC3/6/7 selective, pho...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775509/ https://www.ncbi.nlm.nih.gov/pubmed/33391284 http://dx.doi.org/10.3389/fimmu.2020.613194 |