TLR4 Targeting as a Promising Therapeutic Strategy for Alzheimer Disease Treatment

Alzheimer disease (AD) is a devastating neurodegenerative disorder characterized by extracellular accumulation of amyloid-beta and formation of intracellular neurofibrillary tangles. Microglia activation and neuroinflammation play important roles in the pathogenesis of AD; Toll-like receptor 4 (TLR4...

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Detalles Bibliográficos
Autores principales: Zhou, Yongji, Chen, Yanxing, Xu, Congcong, Zhang, Hao, Lin, Caixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775514/
https://www.ncbi.nlm.nih.gov/pubmed/33390886
http://dx.doi.org/10.3389/fnins.2020.602508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775514/
https://www.ncbi.nlm.nih.gov/pubmed/33390886
http://dx.doi.org/10.3389/fnins.2020.602508

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