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Suppression of mI(CAT) in Mouse Small Intestinal Myocytes by General Anaesthetic Ketamine and its Recovery by TRPC4 Agonist (-)-englerin A

A better understanding of the negative impact of general anesthetics on gastrointestinal motility requires thorough knowledge of their molecular targets. In this respect the muscarinic cationic current (mI(CAT) carried mainly via TRPC4 channels) that initiates cholinergic excitation-contraction coup...

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Detalles Bibliográficos
Autores principales: Melnyk, Mariia I., Dryn, Dariia O., Al Kury, Lina T., Dziuba, Dmytro O., Zholos, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775583/
https://www.ncbi.nlm.nih.gov/pubmed/33390980
http://dx.doi.org/10.3389/fphar.2020.594882