Low Cerebrospinal Fluid Levels of Hemopexin Are Associated With Increased Alzheimer's Pathology, Hippocampal Hypometabolism, and Cognitive Decline

Brain iron dyshomeostasis is a feature of Alzheimer's disease. Conventionally, research has focused on non-heme iron although degradation of heme from hemoglobin subunits can generate iron to augment the redox-active iron pool. Hemopexin both detoxifies heme to maintain iron homeostasis and bol...

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Detalles Bibliográficos
Autores principales: Ashraf, Azhaar A., Dani, Melanie, So, Po-Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775585/
https://www.ncbi.nlm.nih.gov/pubmed/33392254
http://dx.doi.org/10.3389/fmolb.2020.590979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775585/
https://www.ncbi.nlm.nih.gov/pubmed/33392254
http://dx.doi.org/10.3389/fmolb.2020.590979

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