Multi-parameter Behavioral Phenotyping of the MPP+ Model of Parkinson’s Disease in Zebrafish

Parkinson’s disease (PD) has been modeled in several animal species using the neurotoxins 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its oxidized product 1-methyl-4-phenylpyridinium (MPP+). MPP+ selectively kills dopaminergic neurons in pars compacta of the substantia nigra, inducing pa...

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Detalles Bibliográficos
Autores principales: Christensen, Christian, Þorsteinsson, Haraldur, Maier, Valerie Helene, Karlsson, Karl Ægir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775599/
https://www.ncbi.nlm.nih.gov/pubmed/33390914
http://dx.doi.org/10.3389/fnbeh.2020.623924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775599/
https://www.ncbi.nlm.nih.gov/pubmed/33390914
http://dx.doi.org/10.3389/fnbeh.2020.623924

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