FGIN-1-27 Inhibits Melanogenesis by Regulating Protein Kinase A/cAMP-Responsive Element-Binding, Protein Kinase C-β, and Mitogen-Activated Protein Kinase Pathways

FGIN-1-27 is a synthetic mitochondrial diazepam binding inhibitor receptor (MDR) agonist that has demonstrated pro-apoptotic, anti-anxiety, and steroidogenic activity in various studies. Here we report, for the first time, the anti-melanogenic efficacy of FGIN-1-27 in vitro and in vivo. FGIN-1-27 si...

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Detalles Bibliográficos
Autores principales: Lv, Jinpeng, Jiang, Songzhou, Yang, Ying, Zhang, Ximei, Gao, Rongyin, Cao, Yan, Song, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775666/
https://www.ncbi.nlm.nih.gov/pubmed/33390991
http://dx.doi.org/10.3389/fphar.2020.602889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775666/
https://www.ncbi.nlm.nih.gov/pubmed/33390991
http://dx.doi.org/10.3389/fphar.2020.602889

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