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Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate

The inverse relationship of plasma bilirubin levels with liver fat accumulation has prompted the possibility of bilirubin as a therapeutic for non-alcoholic fatty liver disease. Here, we used diet-induced obese mice with non-alcoholic fatty liver disease treated with pegylated bilirubin (bilirubin n...

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Detalles Bibliográficos
Autores principales: Hinds, Terry D., Creeden, Justin F., Gordon, Darren M., Stec, Donald F., Donald, Matthew C., Stec, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775678/
https://www.ncbi.nlm.nih.gov/pubmed/33390979
http://dx.doi.org/10.3389/fphar.2020.594574