Case Report: Efficacy of Reduced Doses of Asfotase Alfa Replacement Therapy in an Infant With Hypophosphatasia Who Lacked Severe Clinical Symptoms

BACKGROUND: Hypophosphatasia is a rare bone disease characterized by impaired bone mineralization and low alkaline phosphatase activity. Here, we describe the course of bone-targeted enzyme replacement therapy with asfotase alpha for a female infant patient with hypophosphatasia who lacked apparent...

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Detalles Bibliográficos
Autores principales: Fujisawa, Yasuko, Kitaoka, Taichi, Ono, Hiroyuki, Nakashima, Shinichi, Ozono, Keiichi, Ogata, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775725/
https://www.ncbi.nlm.nih.gov/pubmed/33391183
http://dx.doi.org/10.3389/fendo.2020.590455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775725/
https://www.ncbi.nlm.nih.gov/pubmed/33391183
http://dx.doi.org/10.3389/fendo.2020.590455

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