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Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle

Unbalanced energy partitioning participates in the rise of obesity, a major public health concern in many countries. Increasing basal energy expenditure has been proposed as a strategy to fight obesity yet raises efficiency and safety concerns. Here, we show that mice deficient for a muscle-specific...

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Detalles Bibliográficos
Autores principales: Prola, Alexandre, Blondelle, Jordan, Vandestienne, Aymeline, Piquereau, Jérôme, Denis, Raphaël G. P., Guyot, Stéphane, Chauvin, Hadrien, Mourier, Arnaud, Maurer, Marie, Henry, Céline, Khadhraoui, Nahed, Gallerne, Cindy, Molinié, Thibaut, Courtin, Guillaume, Guillaud, Laurent, Gressette, Mélanie, Solgadi, Audrey, Dumont, Florent, Castel, Julien, Ternacle, Julien, Demarquoy, Jean, Malgoyre, Alexandra, Koulmann, Nathalie, Derumeaux, Geneviève, Giraud, Marie-France, Joubert, Frédéric, Veksler, Vladimir, Luquet, Serge, Relaix, Frédéric, Tiret, Laurent, Pilot-Storck, Fanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775760/
https://www.ncbi.nlm.nih.gov/pubmed/33523852
http://dx.doi.org/10.1126/sciadv.abd6322