Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice

Light-inducible gene switches represent a key strategy for the precise manipulation of cellular events in fundamental and applied research. However, the performance of widely used gene switches is limited due to low tissue penetrance and possible phototoxicity of the light stimulus. To overcome thes...

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Detalles Bibliográficos
Autores principales: Schneider, Nils, Wieland, Franz-Georg, Kong, Deqiang, Fischer, Alexandra A. M., Hörner, Maximilian, Timmer, Jens, Ye, Haifeng, Weber, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775772/
https://www.ncbi.nlm.nih.gov/pubmed/33523844
http://dx.doi.org/10.1126/sciadv.abd3568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775772/
https://www.ncbi.nlm.nih.gov/pubmed/33523844
http://dx.doi.org/10.1126/sciadv.abd3568

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