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Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice
Light-inducible gene switches represent a key strategy for the precise manipulation of cellular events in fundamental and applied research. However, the performance of widely used gene switches is limited due to low tissue penetrance and possible phototoxicity of the light stimulus. To overcome thes...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775772/ https://www.ncbi.nlm.nih.gov/pubmed/33523844 http://dx.doi.org/10.1126/sciadv.abd3568 |