Development of a UHPLC-MS/MS method for the quantification of ilaprazole enantiomers in rat plasma and its pharmacokinetic application

In Korea and China, ilaprazole is a widely used proton pump inhibitor in the treatment of gastric ulcers. In this study, a specific and sensitive LC-MS/MS method has been developed and validated for the quantification of ilaprazole enantiomers in the rat plasma, using R-lansoprazole as the internal...

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Detalles Bibliográficos
Autores principales: Ou, Fengting, Zhou, Ying, Lei, Jinxiu, Zeng, Su, Wu, Fuhai, Zhang, Ning, Yu, Lushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775851/
https://www.ncbi.nlm.nih.gov/pubmed/33425456
http://dx.doi.org/10.1016/j.jpha.2019.09.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775851/
https://www.ncbi.nlm.nih.gov/pubmed/33425456
http://dx.doi.org/10.1016/j.jpha.2019.09.002

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