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Development of a UHPLC-MS/MS method for the quantification of ilaprazole enantiomers in rat plasma and its pharmacokinetic application
In Korea and China, ilaprazole is a widely used proton pump inhibitor in the treatment of gastric ulcers. In this study, a specific and sensitive LC-MS/MS method has been developed and validated for the quantification of ilaprazole enantiomers in the rat plasma, using R-lansoprazole as the internal...
Autores principales: | Ou, Fengting, Zhou, Ying, Lei, Jinxiu, Zeng, Su, Wu, Fuhai, Zhang, Ning, Yu, Lushan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775851/ https://www.ncbi.nlm.nih.gov/pubmed/33425456 http://dx.doi.org/10.1016/j.jpha.2019.09.002 |
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