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Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid
Liver injury caused by acetaminophen (AP) overdose is a leading public health problem. Although AP-induced liver injury is well recognized as the formation of N-acetyl-p-benzoquinone (NAPQI), a toxic metabolite of AP, resulting in cell damage, emerging evidence indicates that AP-induced liver injury...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775853/ https://www.ncbi.nlm.nih.gov/pubmed/33425450 http://dx.doi.org/10.1016/j.jpha.2019.11.003 |