Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid

Liver injury caused by acetaminophen (AP) overdose is a leading public health problem. Although AP-induced liver injury is well recognized as the formation of N-acetyl-p-benzoquinone (NAPQI), a toxic metabolite of AP, resulting in cell damage, emerging evidence indicates that AP-induced liver injury...

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Detalles Bibliográficos
Autores principales: Zheng, Ningning, Gu, Yu, Hong, Ying, Sheng, Lili, Chen, Linlin, Zhang, Feng, Hou, Jie, Zhang, Weidong, Zhang, Zean, Jia, Wei, Li, Houkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775853/
https://www.ncbi.nlm.nih.gov/pubmed/33425450
http://dx.doi.org/10.1016/j.jpha.2019.11.003

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