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Challenges for cysteamine stabilization, quantification, and biological effects improvement

The aminothiol cysteamine, derived from coenzyme A degradation in mammalian cells, presents several biological applications. However, the bitter taste and sickening odor, chemical instability, hygroscopicity, and poor pharmacokinetic profile of cysteamine limit its efficacy. The use of encapsulation...

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Detalles Bibliográficos
Autores principales: Atallah, Carla, Charcosset, Catherine, Greige-Gerges, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775854/
https://www.ncbi.nlm.nih.gov/pubmed/33425447
http://dx.doi.org/10.1016/j.jpha.2020.03.007