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Methods for quantitative susceptibility and R2* mapping in whole post-mortem brains at 7T applied to amyotrophic lateral sclerosis

Susceptibility weighted magnetic resonance imaging (MRI) is sensitive to the local concentration of iron and myelin. Here, we describe a robust image processing pipeline for quantitative susceptibility mapping (QSM) and R2* mapping of fixed post-mortem, whole-brain data. Using this pipeline, we comp...

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Detalles Bibliográficos
Autores principales: Wang, Chaoyue, Foxley, Sean, Ansorge, Olaf, Bangerter-Christensen, Sarah, Chiew, Mark, Leonte, Anna, Menke, Ricarda AL, Mollink, Jeroen, Pallebage-Gamarallage, Menuka, Turner, Martin R, Miller, Karla L, Tendler, Benjamin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7775972/
https://www.ncbi.nlm.nih.gov/pubmed/32745677
http://dx.doi.org/10.1016/j.neuroimage.2020.117216