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27. The Membrane Antimicrobial Peptide Defense (MadRS) System Orchestrates Resistance Against Antibiotics and Host Innate Immune Peptides in enterococcus Faecalis

BACKGROUND: Enterococci have evolved a network of two component-signaling systems (TCS) to evade killing by cationic antimicrobial peptides (AP) of the host innate immune response. Activation of these pathways can also lead to cross-resistance to AP-like antibiotics such as daptomycin (DAP), complic...

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Detalles Bibliográficos
Autores principales: Miller, William R, Khan, Ayesha, Erickson, Samuel G, Pettaway, Cedric H, Rios, Rafael, Cruz, Melissa R, Dinh, An Q, Diaz, Lorena, Garsin, Danielle A, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776013/
http://dx.doi.org/10.1093/ofid/ofaa417.026