Autoantibody-mediated desialylation impairs human thrombopoiesis and platelet lifespan

Immune thrombocytopenia is a common bleeding disease caused by autoantibody-mediated accelerated platelet clearance and impaired thrombopoiesis. Accumulating evidence suggests that desialylation affects platelet lifespan in immune thrombocytopenia. Herein, we report on novel effector functions of au...

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Detalles Bibliográficos
Autores principales: Marini, Irene, Zlamal, Jan, Faul, Christoph, Holzer, Ursula, Hammer, Stefanie, Pelzl, Lisann, Bethge, Wolfgang, Althaus, Karina, Bakchoul, Tamam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776251/
https://www.ncbi.nlm.nih.gov/pubmed/31857361
http://dx.doi.org/10.3324/haematol.2019.236117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776251/
https://www.ncbi.nlm.nih.gov/pubmed/31857361
http://dx.doi.org/10.3324/haematol.2019.236117

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