Upregulation of endothelial cell-derived exosomal microRNA-125b-5p protects from sepsis-induced acute lung injury by inhibiting topoisomerase II alpha

OBJECTIVE: Emerging evidence has revealed that exosomal microRNAs (miRNAs) are implicated in human diseases. However, role of exosomal miR-125b-5p in sepsis-induced acute lung injury (ALI) remains further explored. We focused on the effect of exosomal miR-125b-5p on ALI progression via targeting top...

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Detalles Bibliográficos
Autores principales: Jiang, Lijing, Ni, Jindi, Shen, Guofeng, Xia, Zhuye, Zhang, Lu, Xia, Shihong, Pan, Shengfu, Qu, Hongping, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776283/
https://www.ncbi.nlm.nih.gov/pubmed/33386874
http://dx.doi.org/10.1007/s00011-020-01415-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776283/
https://www.ncbi.nlm.nih.gov/pubmed/33386874
http://dx.doi.org/10.1007/s00011-020-01415-0

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