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Emerging epigenetic therapeutics for myeloid leukemia: modulating demethylase activity with ascorbate
The past decade has seen a proliferation of drugs that target epigenetic pathways. Many of these drugs were developed to treat acute myeloid leukemia, a condition in which dysregulation of the epigenetic landscape is well established. While these drugs have shown promise, critical issues persist. Sp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Fondazione Ferrata Storti
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776339/ https://www.ncbi.nlm.nih.gov/pubmed/33099992 http://dx.doi.org/10.3324/haematol.2020.259283 |