1276. Evaluation of CD377, a Novel Antiviral Fc-Conjugate (AVC), In Vitro Activity and In Vivo Efficacy in Immune-Competent and -Deficient (SCID) Lethal Mouse Models

BACKGROUND: Cidara’s AVCs are novel, potent, antiviral agents conjugated with the Fc domain of human IgG1. CD377 is an AVC development candidate being evaluated for prevention and treatment of seasonal and pandemic influenza, including in immune-deficient populations unable to benefit from vaccinati...

Descripción completa

Detalles Bibliográficos
Autores principales: Levin, James, Amundson, Karin, Borchardt, Allen, Lam, Thanh, Brady, Tom, Abelovski, Elizabeth, Döhrmann, Simon, Cole, Jason, Ong, Voon, Tari, Les
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776346/
http://dx.doi.org/10.1093/ofid/ofaa439.1460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776346/
http://dx.doi.org/10.1093/ofid/ofaa439.1460

Ejemplares similares