162. CD377, a Novel Antiviral Fc-conjugate, Demonstrates Potent Viral Burden Reduction Against Influenza a (H1N1) in Mouse and Ferret Models

BACKGROUND: AVCs (antiviral Fc-conjugates) are novel, long-acting immunotherapeutic conjugates of potent antivirals conjugated to the Fc domain of human IgG1. CD377, an AVC development candidate for the prevention and treatment of influenza A and B, comprises multiple copies of a novel neuraminidase...

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Detalles Bibliográficos
Autores principales: Döhrmann, Simon, Almaguer, Amanda, Dedeic, Nicholas, Amundson, Karin, Shathia, Kim, Brady, Thomas P, Noncovich, Alain, Zhao, Qiping, Hough, Grayson, Borchardt, Allen, Locke, Jeffrey B, Cole, Jason, Levin, James, Tari, Les
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776402/
http://dx.doi.org/10.1093/ofid/ofaa439.472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776402/
http://dx.doi.org/10.1093/ofid/ofaa439.472

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