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FXR mediates T cell-intrinsic responses to reduced feeding during infection

Reduced nutrient intake is a widely conserved manifestation of sickness behavior with poorly characterized effects on adaptive immune responses. During infectious challenges, naive T cells encountering their cognate antigen become activated and differentiate into highly proliferative effector T cell...

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Detalles Bibliográficos
Autores principales: Campbell, Clarissa, Marchildon, Francois, Michaels, Anthony J., Takemoto, Naofumi, van der Veeken, Joris, Schizas, Michail, Pritykin, Yuri, Leslie, Christina S., Intlekofer, Andrew M., Cohen, Paul, Rudensky, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776647/
https://www.ncbi.nlm.nih.gov/pubmed/33318189
http://dx.doi.org/10.1073/pnas.2020619117