1281. Longitudinal and Spatial Variation in the Human Microbiome in a Phase 2a Clinical Study of Gepotidacin in Adult Females with Uncomplicated Urinary Tract Infection

BACKGROUND: Gepotidacin (GSK2140944) is a first in class novel oral triazaacenaphthylene bacterial topoisomerase inhibitor. In this study, we evaluated the potential impact of orally administered gepotidacin on the human microbiome, across three body-sites and at three specific time-points, as an ex...

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Detalles Bibliográficos
Autores principales: Nuzzo, Andrea, Van Horn, Stephanie, Traini, Christopher, Perry, Caroline R, Dumont, Etienne, Scangarella-Oman, Nicole, Gardiner, David, Brown, James R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776697/
http://dx.doi.org/10.1093/ofid/ofaa439.1464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776697/
http://dx.doi.org/10.1093/ofid/ofaa439.1464

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