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1237. Robust Adjuvant Activity and Dose-sparing Potential of the Novel Semisynthetic Saponin Adjuvant TQL1055 for Seasonal and Pandemic Influenza

BACKGROUND: Vaccination against both seasonal and pandemic influenza requires effective adjuvants to maximize the utility of limited antigen and to enhance immunogenicity in hyporesponsive at-risk populations. First-generation natural saponins are potent immuno-enhancers but are reactogenic and have...

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Detalles Bibliográficos
Autores principales: Buzz, Chloe, Farris, Eric, Bennett, Sean R, Frenchick, Pat, Martin, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776768/
http://dx.doi.org/10.1093/ofid/ofaa439.1422