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Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing
The ability to accurately measure mutations is critical for basic research and identifying potential drug and chemical carcinogens. Current methods for in vivo quantification of mutagenesis are limited because they rely on transgenic rodent systems that are low-throughput, expensive, prolonged, and...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776782/ https://www.ncbi.nlm.nih.gov/pubmed/33318186 http://dx.doi.org/10.1073/pnas.2013724117 |