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1311. Intrapulmonary Pharmacokinetics of Cefiderocol in Hospitalized and Ventilated Patients Receiving Standard of Care Antibiotics for Bacterial Pneumonia

BACKGROUND: Cefiderocol (CFDC), a novel siderophore cephalosporin, has potent in vitro activity against Gram-negative bacteria causing nosocomial pneumonia (NP). The non-inferiority of CFDC to meropenem in Day 14 all-cause mortality in NP was previously demonstrated. In this study, we assessed the i...

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Detalles Bibliográficos
Autores principales: Katsube, Takayuki, Wajima, Toshihiro, Echols, Roger, Portsmouth, Simon, Ariyasu, Mari, Rodvold, Keith, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776793/
http://dx.doi.org/10.1093/ofid/ofaa439.1493