1304. Characterization of Tebipenem Pivoxil Hydrobromide Pharmacokinetics-Pharmacodynamics (PK-PD) in a Neutropenic Murine Acute Pyelonephritis (AP) Model

BACKGROUND: Tebipenem pivoxil hydrobromide (tebipenem HBr), an orally (PO) bioavailable prodrug of tebipenem, is a carbapenem with broad-spectrum activity against Gram-positive and -negative bacteria that is being developed for the treatment of patients with complicated urinary tract infections, inc...

Descripción completa

Detalles Bibliográficos
Autores principales: VanScoy, Brian D, Fikes, Steven, Rubino, Christopher M, Bhavnani, Sujata M, Cotroneo, Nicole S, Critchley, Ian A, Parr, Thomas R, Ambrose, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776801/
http://dx.doi.org/10.1093/ofid/ofaa439.1487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776801/
http://dx.doi.org/10.1093/ofid/ofaa439.1487

Ejemplares similares