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1271. Efficacy and Safety of Cefiderocol and Best Available Therapy in Patients with Serious Infections Caused by Carbapenem-Resistant Gram-Negative Infections: Results of the Pathogen-Focused Phase 3 CREDIBLE-CR Study

BACKGROUND: The CREDIBLE-CR study assessed the efficacy and safety of cefiderocol (CFDC), a novel siderophore cephalosporin, in the treatment of serious infections due to carbapenem-resistant (CR) Gram-negative (GN) bacteria. METHODS: CREDIBLE-CR was an open-label, prospective, randomized 2:1, Phase...

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Detalles Bibliográficos
Autores principales: Bassetti, Matteo, Echols, Roger, Matsunaga, Yuko, Portsmouth, Simon, Ariyasu, Mari, Toyoizumi, Kiichiro, Doi, Yohei, Den Nagata, Tsutae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776890/
http://dx.doi.org/10.1093/ofid/ofaa439.1455