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1279. In Vitro Activity of Nacubactam (OP0595) Alone and in Combination with β-Lactams against β-Lactamase-Producing Enterobacterales Isolated in Japan

BACKGROUND: Nacubactam (NAC) is a novel serine β-lactamase inhibitor in clinical development, and inhibits Ambler class A, class C, and some class D β-lactamases. In addition, it has penicillin-binding protein (PBP) 2-dependent antibacterial activity and an ‘enhancer’ effect when combined with β-lac...

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Detalles Bibliográficos
Autores principales: Nagira, Yu, Yamada, Keiko, Okade, Hayato, Senju, Nami, Tsutsumi, Yuko, Tabata, Yuji, Kato, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776921/
http://dx.doi.org/10.1093/ofid/ofaa439.1462