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1191. Evolution of Hepatitis C Virus Points to Postpartum Recovery of CD8+ T-Cell Selection Pressure

BACKGROUND: In acute persisting hepatitis C virus (HCV) infection, brief control of viral replication can occur with onset of a cellular immune response but is eventually lost due to selection of viral variants with escape mutations in CD8 T cell epitopes or development of T cell exhaustion. In chro...

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Detalles Bibliográficos
Autores principales: Smith, Stephanie, Xu, Zhaohui, Walker, Christopher, Honegger, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777035/
http://dx.doi.org/10.1093/ofid/ofaa439.1376