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1191. Evolution of Hepatitis C Virus Points to Postpartum Recovery of CD8+ T-Cell Selection Pressure
BACKGROUND: In acute persisting hepatitis C virus (HCV) infection, brief control of viral replication can occur with onset of a cellular immune response but is eventually lost due to selection of viral variants with escape mutations in CD8 T cell epitopes or development of T cell exhaustion. In chro...
Autores principales: | Smith, Stephanie, Xu, Zhaohui, Walker, Christopher, Honegger, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777035/ http://dx.doi.org/10.1093/ofid/ofaa439.1376 |
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