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An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease

Streptococcus pneumoniae (Spn) colonizes the nasopharynx and can cause pneumonia. From the lungs it spreads to the bloodstream and causes organ damage. We characterized the in vivo Spn and mouse transcriptomes within the nasopharynx, lungs, blood, heart, and kidneys using three Spn strains. We ident...

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Detalles Bibliográficos
Autores principales: D’Mello, Adonis, Riegler, Ashleigh N., Martínez, Eriel, Beno, Sarah M., Ricketts, Tiffany D., Foxman, Ellen F., Orihuela, Carlos J., Tettelin, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777036/
https://www.ncbi.nlm.nih.gov/pubmed/33318198
http://dx.doi.org/10.1073/pnas.2010428117