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1273. Efficacy of Cefiderocol against carbapenem-resistant A. baumannii and P. aeruginosa in ventilator-associated pneumonia mouse model

BACKGROUND: Cefiderocol (CFDC) is a novel cephalosporin with siderophore structure, characterized by transportation through siderophore receptor on outer membrane of Gram-negative bacteria and structural stability against beta-lactamase. The antimicrobial activity against multidrug resistant bacteri...

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Detalles Bibliográficos
Autores principales: Ota, Kenji, Kaku, Norihito, Uno, Naoki, Sakamoto, Kei, Kosai, Kosuke, Hasegawa, Hiroo, Miyazaki, Taiga, Izumikawa, Koichi, Mukae, Hiroshi, Yanagihara, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777080/
http://dx.doi.org/10.1093/ofid/ofaa439.1457