Quinine copolymer reporters promote efficient intracellular DNA delivery and illuminate a protein-induced unpackaging mechanism

Polymeric vehicles that efficiently package and controllably release nucleic acids enable the development of safer and more efficacious strategies in genetic and polynucleotide therapies. Developing delivery platforms that endogenously monitor the molecular interactions, which facilitate binding and...

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Detalles Bibliográficos
Autores principales: Van Bruggen, Craig, Punihaole, David, Keith, Allison R., Schmitz, Andrew J., Tolar, Jakub, Frontiera, Renee R., Reineke, Theresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777095/
https://www.ncbi.nlm.nih.gov/pubmed/33318196
http://dx.doi.org/10.1073/pnas.2016860117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777095/
https://www.ncbi.nlm.nih.gov/pubmed/33318196
http://dx.doi.org/10.1073/pnas.2016860117

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