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Quinine copolymer reporters promote efficient intracellular DNA delivery and illuminate a protein-induced unpackaging mechanism
Polymeric vehicles that efficiently package and controllably release nucleic acids enable the development of safer and more efficacious strategies in genetic and polynucleotide therapies. Developing delivery platforms that endogenously monitor the molecular interactions, which facilitate binding and...
Autores principales: | Van Bruggen, Craig, Punihaole, David, Keith, Allison R., Schmitz, Andrew J., Tolar, Jakub, Frontiera, Renee R., Reineke, Theresa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777095/ https://www.ncbi.nlm.nih.gov/pubmed/33318196 http://dx.doi.org/10.1073/pnas.2016860117 |
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