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1440. The Genetic Basis for a Neisseria gonorrhoeae Clinical Isolate That Contains mtrR(-79) Mutation But Is Highly Susceptible to Antibiotics Effluxed by the Mtr Pump System

BACKGROUND: Neisseria gonorrhoeae (NG) possesses multiple drug efflux systems that play an important role in evading antibiotics in the treatment for gonorrhea and in helping this pathogen to evade innate antimicrobial defenses during infection. The mtrR(-79) and mtr(120) mutations in the promoter r...

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Detalles Bibliográficos
Autores principales: Huang, Jianzhong, Ingraham, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777145/
http://dx.doi.org/10.1093/ofid/ofaa439.1621