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Widespread occurrence of the droplet state of proteins in the human proteome

A wide range of proteins have been reported to condensate into a dense liquid phase, forming a reversible droplet state. Failure in the control of the droplet state can lead to the formation of the more stable amyloid state, which is often disease-related. These observations prompt the question of h...

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Detalles Bibliográficos
Autores principales: Hardenberg, Maarten, Horvath, Attila, Ambrus, Viktor, Fuxreiter, Monika, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777240/
https://www.ncbi.nlm.nih.gov/pubmed/33318217
http://dx.doi.org/10.1073/pnas.2007670117