Cargando…
Widespread occurrence of the droplet state of proteins in the human proteome
A wide range of proteins have been reported to condensate into a dense liquid phase, forming a reversible droplet state. Failure in the control of the droplet state can lead to the formation of the more stable amyloid state, which is often disease-related. These observations prompt the question of h...
Autores principales: | Hardenberg, Maarten, Horvath, Attila, Ambrus, Viktor, Fuxreiter, Monika, Vendruscolo, Michele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777240/ https://www.ncbi.nlm.nih.gov/pubmed/33318217 http://dx.doi.org/10.1073/pnas.2007670117 |
Ejemplares similares
-
Sequence-based prediction of protein binding mode landscapes
por: Horvath, Attila, et al.
Publicado: (2020) -
Sequence-based
Prediction of the Cellular Toxicity
Associated with Amyloid Aggregation within Protein Condensates
por: Horvath, Attila, et al.
Publicado: (2022) -
Protein condensation diseases: therapeutic opportunities
por: Vendruscolo, Michele, et al.
Publicado: (2022) -
Multiomic prediction of therapeutic targets for human diseases associated with protein phase separation
por: Lim, Christine M., et al.
Publicado: (2023) -
Extant fold-switching proteins are widespread
por: Porter, Lauren L., et al.
Publicado: (2018)