1238. The Novel Semisynthetic Saponin Adjuvant TQL1055 Enhances the Antibody Response to Pertussis Vaccine with an Improved Tolerability Profile over QS-21

BACKGROUND: Acellular pertussis vaccines are better tolerated but less immunogenic than older whole cell vaccines. Novel adjuvants may be useful to enhance their immunogenicity. First-generation natural saponins are potent immuno-enhancers but are highly reactogenic. The novel semisynthetic saponin...

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Detalles Bibliográficos
Autores principales: Buzz, Chloe, Ragupathi, Govind, Bennett, Sean R, Livingston, Phil, Farris, Eric, Martin, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777340/
http://dx.doi.org/10.1093/ofid/ofaa439.1423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777340/
http://dx.doi.org/10.1093/ofid/ofaa439.1423

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