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1295. Activity of SPR206, a Polymyxin B Derivative, Compared to Colistin Alone and in Combination Against Multidrug-Resistant Pseudomonas aeruginosa Strains

BACKGROUND: The emergence of multidrug-resistant (MDR) Pseudomonas aeruginosa strains, has resulted in the use of previously discarded antibiotics, such as the polymyxins (polymyxin B and colistin (COL)). Consequently, the polymyxins are continually characterized by the cytotoxicity associated with...

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Detalles Bibliográficos
Autores principales: Abdul-Mutakabbir, Jacinda C, Nguyen, Logan, Stamper, Kyle, Maassen, Philip, Lev, Katherine, Morrisette, Taylor, Kebriaei, Razieh, Rybak, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777375/
http://dx.doi.org/10.1093/ofid/ofaa439.1478