1299. In Vitro-In Vivo Discordance with β-lactams against Metallo-β-lactamase-Producing Enterobacterales: Implications for Susceptibility Testing

BACKGROUND: Using murine models of thigh and lung infection, we previously reported the potent in vivo activity of carbapenem human-simulated regimens against metallo-β-lactamase-producing Enterobacterales despite the observed resistance in vitro (JAC 2020 Apr 1;75(4):997-1005, AAC 2014;58(3):1671-7...

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Detalles Bibliográficos
Autores principales: Abdelraouf, Kamilia, Reyes, Sergio, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777513/
http://dx.doi.org/10.1093/ofid/ofaa439.1482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777513/
http://dx.doi.org/10.1093/ofid/ofaa439.1482

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