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194. Combinatorial Polyfunctionality Analysis of Antigen-specific T-cell Subsets (COMPASS) as a Predictor for Clinically Significant CMV Infection in the Letermovir Era

BACKGROUND: Increased CMV reactivation is observed following discontinuation of letermovir prophylaxis after hematopoietic cellular transplantation (HCT) and decreased CMV-specific polyfunctional T-cell immunity has been proposed as a possible mechanism (BBMT 2020;26:S68). COMPASS is a novel analyti...

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Detalles Bibliográficos
Autores principales: Zamora, Danniel, Duke, Elizabeth, Xie, Hu, Edmison, Bradley, Akoto, Brenda, Kiener, Richard, Stevens-Ayers, Terry, Wagner, Ralf, Mielcarek, Marco, Schiffer, Joshua, De Rosa, Stephen, Boeckh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7777534/
http://dx.doi.org/10.1093/ofid/ofaa439.504